Medicaments are pharmaceuticals used with injectors to produce game effects on characters. In order to be used, Medicaments must be applied either using an injector or by a Physician using appropriate roleplaying equipment.

Medicaments are represented in-game with a tear-edge lammie. The lammie will indicate its effects on the back, and also has a space to stick Exotic Substances stickers to. While the medicament is taking effect or still in effect, you should retain the lammies for any medicaments you have taken.

The term Medicaments became preferred over pharmaceuticals in the first few centuries of the Ascendancy, when the aggressively Francophone House Clervoy, who produced the majority of drugs at the time, insisted on the term for all of their pharmaceutical products. In the intervening period, the term has stuck and become the standard term for translator technology.

At events, various Medicaments can usually be purchased from one or more MegaCorps, typically those with an interest in biotech (such as Lazarus Corporation) or equipment (such as Advanced Armaments).